Video-Can the 49ers keep up with the Saints?
 

2 things can stop the Saints:

1) The Saints - if Drew comes out cold, defense is weak against stopping the run, WR drops...

2) 49ers - use total ball control, eat up all time on the clock and Drew is off the field.

Worst case - Even if the game is slowed down, Drew can keep the Saints in the game.

If the 49ers make a mistake, turnover (and they are DUE for some but don't turn the ball over much) and the Saints get ahead, it could be a long day in the Bay.