Starting to think NFL season not feasible

AsylumGuido · 06-20-2020, 06:06 PM

Originally Posted by hitta

Antibodies dropping a few weeks after infection does not mean you are open to infection. The immune system doesn't work that way. While there are potential ways that infection could occur, I'd guess that they are rare circumstances. Of course, there may be something unique about the virus that causes our immune system to do something strange or mutations may occur or something... that's possible. For the most part though, there's not really any real evidence that reinfection occurs.

Mutations could possibly reinfect, but mutations are likely to be more infectious, but far less invasive. That is the pattern of virus spread. In other words, it is possible to contract a variation but is is most likely it will be far less intrusive or even symptomatic at all.

hitta · 06-20-2020, 06:38 PM

Originally Posted by AsylumGuido

Mutations could possibly reinfect, but mutations are likely to be more infectious, but far less invasive. That is the pattern of virus spread. In other words, it is possible to contract a variation but is is most likely it will be far less intrusive or even symptomatic at all.

For a mutation to cause reinfection, it'd have to be one that changed its spike proteins, which is the epitope that the neutralizing antibody attaches too. The virus is not really mutating that rapidly of a pace, much slower than influenza viruses do. Covid-19 is more sophisticated than than influenza, has better error checking mechanisms etc... which ironically make it less likely to mutate. It could happen, but it's very doubtful.

06-20-2020, 06:06 PM	#1
AsylumGuido 10000 POST CLUB Join Date: Sep 2007 Location: Bossier City, LA Posts: 26,622	Re: Starting to think NFL season not feasible Originally Posted by hitta Antibodies dropping a few weeks after infection does not mean you are open to infection. The immune system doesn't work that way. While there are potential ways that infection could occur, I'd guess that they are rare circumstances. Of course, there may be something unique about the virus that causes our immune system to do something strange or mutations may occur or something... that's possible. For the most part though, there's not really any real evidence that reinfection occurs. Mutations could possibly reinfect, but mutations are likely to be more infectious, but far less invasive. That is the pattern of virus spread. In other words, it is possible to contract a variation but is is most likely it will be far less intrusive or even symptomatic at all.

06-20-2020, 06:38 PM	#2
hitta 1000 Posts + Join Date: Oct 2009 Posts: 1,339	Re: Starting to think NFL season not feasible Originally Posted by AsylumGuido Mutations could possibly reinfect, but mutations are likely to be more infectious, but far less invasive. That is the pattern of virus spread. In other words, it is possible to contract a variation but is is most likely it will be far less intrusive or even symptomatic at all. For a mutation to cause reinfection, it'd have to be one that changed its spike proteins, which is the epitope that the neutralizing antibody attaches too. The virus is not really mutating that rapidly of a pace, much slower than influenza viruses do. Covid-19 is more sophisticated than than influenza, has better error checking mechanisms etc... which ironically make it less likely to mutate. It could happen, but it's very doubtful. AsylumGuido, SmashMouth and Rugby Saint II like this.
hitta 1000 Posts + Join Date: Oct 2009 Posts: 1,339